Landon who lost in a landslide to F.D.R. NYT crossword answer is:
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Landon, who ran for president in 1936, lost in a landslide to Franklin D. Roosevelt. Landon, who was the Republican nominee, won only two states in the election, Maine and Vermont, while Roosevelt won the remaining 48 states. This landslide victory for Roosevelt was a sign of the changing political landscape in the United States, as the New Deal policies of the Roosevelt administration began to take hold.